"Why don't you invite him over. Turn him from an enemy to a friend. Then when he's not expecting it -- bam! -- the ol' fork in the eye."

Simpsons Top 100 Countdown
#29 Homer’s Enemy
Season 8, Episode 24 (Guide from the Simpsons Archive)

Seeing a moving story on the tv news about Frank Grimes, a man who has struggled through life, but still managed to get a degree in nuclear physics due to his perseverance, Mr. Burns asks Smithers to fetch him to make him his executive vice president. By the time he arrives, Burns has seen another moving story about a dog, and wishes to give him the EVP position instead, leaving Grimes with more of an entry-level position. Grimes meets Homer and is shocked by his incompetence, sloth, and general aptitude for annoyance. After several run-ins with Homer, Grimes tricks him into joining a power plant design contest for children, hoping to make a fool out of him before the entire company. His plan backfires when Homer wins first prize, which drives Grimes insane, resulting in his death by electrocution. Memorable moments include the news story about Grimes, Grimes’s first meeting with Burns, chair spinning, the gang meeting Grimes, Bart’s purchase, hiring Milhouse, lunch stealing, sulfuric acid, Grimes’s second meeting with Burns, Homer’s plan, photos, Grimes’s living situation, factory’s end, Grimes’s plan, Homer leaving work, basement work, the competition, descent into madness, and the funeral.